Category Archives: The Rheuma Muse

The 9 Muses are daughters of Zeus and Mnemosyne, Greek goddesses personifying the inspiration for the sciences and the arts.
My highly opinionated news-blog draws inspiration from both the science and the art of Rheumatology.

Paternal DMARDs Use in Pregnancy

Risk of Paternal Exposure to Anti-Rheumatic Drugs Seminars in Arthritis and Rheumatism features a review of the effects of paternal use of antirheumatic drugs on pregnancy, specifically addressing the effects of… Mycophenolate mofetil, mycophenolic acid: updated contraception advice for male patients - GOV.UK Mycophenolate mofetil and its active metabolite mycophenolic acid, both used to…
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Biologics in Pregnancy

Patterns of Biologic Use During Autoimmune Pregnancy While it is highly desirable to avoid medications during conception and pregnancy, statistics show that >90% of women take at least one drug during pregnancy and… Biologic use during pregnancy had no impact on serious infection risks in infants Data provide some reassurance for clinicians who are…
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Leflunomide in Pregnancy

Leflunomide use during pregnancy and the risk of adverse pregnancy outcomes Objectives Leflunomide is known to be embryotoxic and teratogenic in rodents. However, there is less evidence in humans. We quantified the risk of major… Compared to other conventional DMARDs (deemed "safe" in pregnancy), biological DMARDs, corticosteroids and NSAIDs, Leflunomide did not increase the…
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Corticosteroid in Pregnancy

Steroid Use During Rheumatoid Pregnancies Pregnant women (n=254) with rheumatoid arthritis who enrolled in the MotherToBaby Autoimmune Diseases…
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